Question 1

Does African mango really work for weight loss?

Accepted Answer

The evidence is weak. Small trials reported significant weight loss [2], but a 2013 systematic review of 208 people found the studies too flawed to recommend it [3]. Some people report mild appetite control, likely from the soluble fiber.

Question 2

What is IGOB131?

Accepted Answer

IGOB131 is a patented, standardized seed extract of Irvingia gabonensis used in the main human trial at 300 mg per day [2]. It is not the same as generic African mango powder.

Question 3

What is the best dose?

Accepted Answer

The studied dose is 300 mg per day, split as 150 mg before two meals, taken 30 to 60 minutes before eating [2].

Question 4

What are the side effects?

Accepted Answer

Headache, gas, trouble sleeping, and constipation, mostly at rates close to placebo in trials [1][3]. One case report linked it to kidney issues in a person who already had kidney disease [1].

Question 5

Is it safe for my kidneys?

Accepted Answer

If you have any kidney condition, do not take it without medical clearance, because of that case report [1].

Question 6

Can I stack it with Cissus quadrangularis?

Accepted Answer

One trial paired them and reported 11.8% body weight loss [8], but the study was small and some users report headaches from the combination [11]. Ask your doctor first.

Question 7

Is African mango FDA approved for weight loss?

Accepted Answer

No. The FDA regulates supplements differently from drugs, so safety and quality are not guaranteed before sale [1].

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