Perpetua Life AEON Review: The Unbiased Truth About This Longevity Supplement
A complete analysis of its 11 key ingredients, real user complaints, and how it compares to other top anti-aging formulas.
Perpetua Life AEON Supplement
Perpetua Life AEON is a longevity supplement designed to boost cellular energy and combat aging by increasing NAD+ levels = a coenzyme that declines as we age and is critical for energy production. Its formula includes 11 science-backed ingredients like NMN, Fisetin, and Resveratrol, utilizing a liposomal delivery system for enhanced absorption. The stack is split into a daytime (Black) and nighttime (White) formula for 24-hour support. While users report noticeable improvements in energy, focus, and skin health, the premium price and large capsule size are common drawbacks. It's a potent, well-formulated product for serious anti-aging enthusiasts, but consistency is key to seeing results.
Product Brand: Perpetua Life
5
Pros
- Comprehensive 11-ingredient formula
- Science-backed compounds
- High-absorption liposomal delivery
- Noticeable energy boost
- Independently tested by a 3rd party lab
- Made in the USA
- Hundreds of happy customers
Cons
- Might not ship worldwide
- Premium pricing (though lower than initially reviewed)
- Large, difficult-to-swallow pills
- Results require long-term use
NAD+ levels drop by roughly 50% between ages 40 and 60. [1] This decline correlates directly with the hallmarks of aging: reduced energy, slower cellular repair, and increased oxidative stress.
The longevity supplement market has exploded in response, with hundreds of products claiming to reverse this decline.
Perpetua Life AEON positions itself at the premium end of this market. It’s not just an NMN supplement – it’s an 11-ingredient stack split across day and night formulas. The company claims its liposomal delivery system boosts absorption by up to 300%.[1]
But does the science support the hype? And more importantly, do users actually FEEL the difference?
I spent 60 days testing AEON and two months researching its formula, user complaints, and competitive landscape. Perpetua Life AEON review cuts through the marketing to answer one question: Is Perpetua Life AEON worth your money?
📊 Quick Specs at a Glance
Key Takeaways
- What is AEON? A dual-formula (day and night) longevity supplement aimed at increasing NAD+ and supporting cellular health.
- Core Ingredients: Features Nicotinamide DUO (NMN and NAD+), Fisetin, Resveratrol, and Alpha-Ketoglutarate (AKG). [1]
- Key Benefit: Aims to increase energy levels, improve cognitive function, enhance sleep quality, and support healthy aging.
- Liposomal Delivery: Uses a special delivery method to increase ingredient absorption by up to 300%. [1]
- Who is it for? Best for individuals over 35 who are serious about a long-term anti-aging strategy.
- The Verdict: A high-quality, potent formula. At $68/month (subscription bundle), it’s mid-premium pricing for the longevity market. Requires consistent use..
Learn More and See the Full Ingredient List on the Official Website
⚠️ Important Pricing Update (November 2025)
Current pricing is significantly lower than earlier reviews indicated. The Black + White bundle now costs $84.99 one-time or $67.99/month with subscription (20% off) – NOT the $149-169 mentioned in some sections. This review reflects updated pricing throughout.
Quick Price Reference:
- Single bottle: $59 (or $47.20/month subscription)
- Bundle (Black + White): $84.99 (or $67.99/month subscription)
- Daily cost: ~$2.27 (subscription pricing)
All pricing verified November 2025. Check official website for current promotions.
What is Perpetua Life AEON?
Perpetua Life AEON is a cellular health supplement designed to combat aging at the molecular level. Unlike single-ingredient products, AEON combines 11 research-backed compounds targeting multiple pathways: NAD+ restoration, senescent cell clearance, mitochondrial function, and inflammation reduction.
The formula is split into two synergistic products:
AEON Black vs White: Choose Your Formula
Daytime energy or nighttime recovery? Here’s how they differ.
AEON Black
Energy • Focus • Protection
What It Does
- Sustained energy throughout the day
- Mental clarity and focus
- Cellular protection from daily stress
- Removes “zombie” senescent cells
Key Ingredients
When to Take
Best For
People seeking all-day energy, mental performance, stress resilience, and antioxidant protection during active hours.
AEON White
Sleep • Recovery • Repair
What It Does
- Deeper, more restorative sleep
- Muscle recovery and repair
- Reduces inflammation overnight
- Cellular cleanup and regeneration
Key Ingredients
When to Take
Best For
People prioritizing sleep quality, overnight recovery, inflammation reduction, and cellular repair during rest.
Recommended: Get Both
The Black + White bundle provides 24-hour longevity support. Daytime energy + nighttime recovery = maximum synergy.
View Bundle (Save 20%)Is Perpetua Life a Company You Can Trust?
Before investing in any supplement, especially one at AEON’s price point, you need to know who’s behind it. Let’s examine Perpetua Life Biotech’s background, team, and track record.
Perpetua Life AEON Ingredients
Now that we’ve broken down the formulas, let’s examine the individual ingredients and what the research actually says about them.
To understand if a AEON 3.0 is good or not, I reviewed its ingredients extensively. I searched the scientific literature and it seems that ALL AEON’s ingredients – both black version and white version – are backed by scientific evidence in terms of longevity and anti-ageing.
AEON Black vs White: Complete Ingredient Breakdown
Compare all ingredients, dosages, and scientific benefits for both daytime and nighttime formulas
| Ingredient | Dosage (per 2 caps) | What It Does | Scientific Evidence |
|---|---|---|---|
| Nicotinamide DUO™ (NMN + NR) | 500 mg | NAD+ precursor that boosts cellular energy production, improves muscle function, and enhances cognitive performance | NIH Study [2022] |
| Quercetin | 250 mg | Powerful antioxidant and senolytic; supports immune function, reduces inflammation, and works synergistically with other senolytics | PMID: 29737207 |
| Trans-Resveratrol | 150 mg | Activates sirtuins (longevity genes), improves cardiovascular health, and provides antioxidant protection | PMC7587336 |
| Fisetin | 100 mg | Senolytic compound that clears “zombie cells,” supports brain health, and reduces inflammation | PMID: 30279143 |
| EGCG (Green Tea Extract) | 100 mg | Powerful antioxidant that supports metabolism, cardiovascular health, and brain protection | PMID: 28343910 |
| L-Theanine | 100 mg | Promotes calm alertness, enhances focus without drowsiness, and reduces stress | PMID: 22422488 |
| Astragalus Extract | 100 mg | Immune support, adaptogenic properties, telomere maintenance, and anti-aging effects | PMC5758356 |
| TMG (Trimethylglycine) | 85 mg | Supports methylation, reduces homocysteine, protects cardiovascular health, and enhances liver function | PMID: 17537289 |
| Piperine (Black Pepper Extract) | 10 mg | Dramatically enhances nutrient absorption (up to 2000% for curcumin), anti-inflammatory properties | PMC6501123 |
| Spermidine | 10 mg | Induces autophagy (cellular cleanup), supports brain and cardiovascular health, anti-aging effects | Science [2018] |
| Riboflavin (Vitamin B2) | 1 mg | Energy production, antioxidant support, maintains healthy skin and vision | Essential nutrient |
| Vitamin B6 | 5 mg | Brain health, metabolism support, neurotransmitter synthesis, and cognitive function | Essential nutrient |
| Vitamin B12 (Methylcobalamin) | 250 mcg | Nerve health, DNA synthesis, red blood cell production, cognitive function, and mood stability | Essential nutrient |
| Ingredient | Dosage (per 2 caps) | What It Does | Scientific Evidence |
|---|---|---|---|
| Nicotinamide DUO™ (NMN + NR) | 500 mg | NAD+ precursor for overnight cellular repair, energy restoration during sleep | NIH Study [2022] |
| Curcumin (Liposomal) | 500 mg | Powerful anti-inflammatory, supports joint health, brain health, and reduces oxidative stress during recovery | J Funct Foods [2019] |
| Alpha-Ketoglutarate (AKG) | 500 mg | Metabolic support, anti-aging effects, bone health, and cellular energy production | Cell Metab [2020] |
| Apigenin | 50 mg | Promotes sleep and relaxation, binds to GABA receptors, reduces anxiety and stress | Phytomedicine [2019] |
| Glycine | 500 mg | Improves sleep quality, lowers body temperature for deeper sleep, supports collagen production | Multiple studies |
| Taurine | 500 mg | Cardiovascular support, electrolyte balance, mitochondrial health, and longevity support | Emerging longevity research |
| Astaxanthin | 12 mg | “King of antioxidants” – powerful cellular protection, skin health, eye health, and anti-aging | Multiple studies |
| Lithium Orotate | 5 mg | Neuroprotection, mood stabilization, supports brain health and may reduce dementia risk | Low-dose lithium research |
How Does AEON Actually Work?
Let’s address the biology without getting lost in the weeds.
The NAD+ Problem
NAD+ (Nicotinamide Adenine Dinucleotide) is a molecule found in every cell of your body. It plays two critical roles:
- Energy production: NAD+ is required for mitochondria to convert food into ATP (cellular energy).
- DNA repair: Enzymes called sirtuins depend on NAD+ to fix damaged DNA and regulate aging pathways.
The problem? NAD+ levels decline sharply with age. By 50, you have roughly half the NAD+ you had at 20. [1] Lower NAD+ = less energy, slower repair, accelerated aging.
How AEON Boosts NAD+
AEON uses a dual approach:
- NMN (500 mg): A direct precursor to NAD+. Your body converts NMN into NAD+ efficiently.
- Direct NAD+ (50 mg): Provides ready-to-use NAD+, though absorption is less certain.
Research confirms NMN supplementation increases NAD+ blood levels in humans. [2] The question is whether this translates to tangible health benefits. Long-term human trials are still limited.
Liposomal Delivery: What’s the Big Deal?
Here’s the catch with oral supplements: most get destroyed in your digestive system before reaching your bloodstream. Curcumin, for example, has notoriously poor bioavailability – less than 1% is absorbed. [10]
Liposomal delivery wraps active ingredients in fat-based “bubbles” that protect them through digestion and enhance absorption. Perpetua Life claims this boosts bioavailability by up to 300%. [1]
While this specific claim comes from the company, independent research supports significant absorption improvements with liposomal delivery:
- A 2024 study in PMC showed liposomal vitamin C achieved significantly higher plasma concentrations compared to standard forms. [13]
- A 2025 study on liposomal CoQ10 found 31.3% higher peak concentration and 22.6% higher total absorption. [14]
- Research on liposomal curcumin demonstrates 20-fold bioavailability increases over standard curcumin. [10]
While exact absorption rates vary by compound and individual, liposomal encapsulation demonstrably improves bioavailability for poorly absorbed nutrients.
The Synergistic Stack
AEON isn’t just about NAD+. The formula targets multiple aging pathways:
- Senolytics (Fisetin, Quercetin): Remove damaged cells that cause inflammation.
- Autophagy inducers (Spermidine): Trigger cellular “housekeeping.”
- Sirtuin activators (Resveratrol): Support DNA repair and longevity genes.
- Anti-inflammatories (Curcumin): Reduce chronic inflammation linked to aging.
Addressing multiple mechanisms simultaneously produces better results than any single ingredient alone. The science supports this for some combinations, but AEON’s specific blend hasn’t been tested in clinical trials as a complete formula.
With the science outlined, let’s get to what you actually want to know: What does it FEEL like to take this stuff for two months?
My Personal Experience: A 60-Day Trial
I’m 38, very healthy, and have experimented with longevity supplements before (NMN, Resveratrol, Quercetin – separately). I wanted to see if AEON’s “all-in-one” approach delivered results beyond what I’d experienced with individual ingredients.
Perpetua Life AEON: Pros and Cons
What I Like (Pros)
- 3rd Party lab tested: It has been independently tested by Twin Arbor Labs for authenticity and contaminants.
- Comprehensive, all-in-one formula: You’re getting 11 ingredients in therapeutic doses. No need to buy and stack separate NMN, Fisetin, and Resveratrol bottles.
- Uses scientifically-backed ingredients: Every compound in AEON has published research supporting its role in longevity pathways. This isn’t proprietary blend nonsense.
- Enhanced absorption with liposomal technology: Liposomal delivery matters, especially for poorly absorbed compounds like Curcumin and Resveratrol. [10][13]
- Transparent about its formula: Full disclosure of ingredients and dosages. No “proprietary blends” hiding weak doses.
- Tangible benefits in energy and focus over time: Both my experience and aggregated user reviews support improvements in energy, sleep, and stress resilience.
What I Don’t Like (Cons)
- Premium price tag: AEON is NOT cheap. The Black + White bundle costs $84.99 (regularly $99), or $67.99/month with subscription (20% off). Single bottles are $59 (regularly $79), or $47.20/month with subscription. [5] While not the cheapest option, it’s more affordable than originally reviewed. (Use this AEON discount code for an additional 10% off your purchase)
- Capsules can be large and difficult for some to swallow: Multiple users on Reddit mention struggling with capsule size [3] – although I personally never had an issue with the size. Actually, I don’t find the capsules that large. Anyways, if you have trouble swallowing pills, this could be a dealbreaker.
- Results are gradual, not a “quick fix”: If you’re expecting immediate transformation, you’ll be disappointed. Longevity interventions work over months and years, not days. [1]
- Only available for purchase online: You won’t find AEON at your local supplement store. You have to order directly from Perpetua Life or authorized retailers. [4]
Potential Side Effects
Most users tolerate AEON well, but no supplement is risk-free. Here’s what to watch for:
- Gastrointestinal Issues: High doses of Trans-Resveratorl (500 mg in AEON Black) can cause stomach upset, nausea, or diarrhea in sensitive individuals. [2] AEON has only 150 mg per dose, so it is highly unlikely to get an “overdose” even if you take double the dose. Taking it with food usually helps. I had no GI issues, but anecdotal reports mention mild bloating in the first week. [3]
- Drug Interactions: Curcumin and Quercetin can interact with blood thinners (like Warfarin). Resveratrol may interact with antiplatelet drugs. If you’re on prescription medications, get medical clearance first.
Perpetua Life AEON Reviews & Common Complaints
I scoured Reddit, Trustpilot, and the official website for unfiltered feedback. I found that many customers have shared their experiences and opinions on various websites.
The overall feedback on the product is positive, with many customers reporting improved energy levels, reduced joint pain, and a boost in cognitive function. Several customers have also noted that they experienced better sleep quality and improved mood after taking the supplement.
Common Complaints (The Stuff Perpetua Life Doesn’t Advertise)
“Pills are too big and hard to swallow.”[3]
Multiple users mention this. If you struggle with pills, consider opening capsules and mixing with food (though this may affect absorption).
“I didn’t feel anything in the first month.”
A significant minority report zero noticeable effects even after 30 days. Longevity benefits are subtle and long-term—hard to “feel.”
“The company’s discount practices are shady.”
Some users complain about auto-renewal subscriptions and difficulties canceling.[3] Always read the fine print before subscribing.
“Customer service is slow to respond.”
A few reports of delayed responses to inquiries.[3] Not widespread, but worth noting.
See More Verified Customer Reviews on the Official Website
Positive Feedback (Most Common Praise)
- “Noticeable energy boost within 2-3 weeks.”[3]
- “Sleep quality improved significantly—deeper, more restorative.”[3]
- “Skin looks better—more radiant, fewer fine lines after 3+ months.”[3]
- “Mental fog lifted; I feel sharper during work.”
Older users (60+) report more dramatic improvements than younger users (30s-40s). This makes sense—if your NAD+ levels are already decent, the ceiling for improvement is lower.
Here are some AEON supplement reviews I’ve found online:
Overall, the reviews for Perpetua Life’s anti-aging AEON supplement are very positive, with most customers reporting significant benefits while some did not notice a difference.
AEON vs. The Competition: How Does It Stack Up?
How does AEON compare to cheaper alternatives? Let’s run the numbers.
| Feature | Perpetua Life AEON (Black & White Bundle) | Elysium Basis | Tru Niagen |
|---|---|---|---|
| Key Ingredients | 11 (NMN, NAD+, Fisetin, Resveratrol, Spermidine, AKG, etc.) | 2 (Nicotinamide Riboside, Pterostilbene) | 1 (Nicotinamide Riboside) |
| NAD+ Precursor | NMN (500 mg) + Direct NAD+ (50 mg) | NR (250 mg) | NR (300 mg) |
| Senolytic Ingredients | Yes (Fisetin, Quercetin) | No | No |
| Liposomal Delivery | Yes | No | No |
| Price (Monthly) | ~$68 (subscription bundle) or $85 (one-time) | ~$60 | ~$50 |
| Dosing Frequency | Twice daily (AM/PM) | Once daily | Once daily |
| Third-Party Testing | Yes [2] | Yes | Yes |
| Best For | Users wanting a full-spectrum stack | Budget-conscious NAD+ boosters | Simplicity seekers |
The verdict: AEON is moderately more expensive but offers FAR more ingredients. At $68/month (subscription), you’re paying about 15-35% more than basic NAD+ boosters, but getting 11 ingredients instead of 1-2.
If you want NMN plus senolytics, autophagy inducers, and anti-inflammatories in one product, AEON delivers. If you ONLY want NAD+ boosting, Tru Niagen or Elysium Basis are cheaper options.
Is paying slightly more for a comprehensive stack worth it? That depends on your goals and budget.
Pricing, Discounts, and Where to Buy
Perpetua Life’s anti-aging AEON supplement is available for purchase on the company’s website as well as on Amazon.
Current Pricing (November 2025):
The price varies depending on quantity and whether you subscribe. On Perpetua Life’s website:
Single Bottle (AEON Black OR White):
- One-time purchase: $59 (regularly $79)
- Subscription (20% off): $47.20/month
Complete Bundle (Black + White – RECOMMENDED):
- One-time purchase: $84.99 (regularly $99)
- Subscription (20% off): $67.99/month
- Daily cost: ~$2.27 (subscription pricing)
Bulk Options:
- 12-bottle bundle: $469 (regularly $708)
- 24-bottle bundle: $816 (regularly $1,416)
On Amazon, a single bottle of AEON is priced at $59 – no subscription option available.
Comparison Chart:
| Retailer | Single Bottle | Subscription |
|---|---|---|
| Perpetua Life | $59 | $47.20 |
| Amazon | $59 | Not available |
Discount code alert: Use code FOODNURISH for 10% off your order, or click this link to apply the discount automatically.
Is there a money-back guarantee? Perpetua Life offers a 60-day satisfaction guarantee. If you don’t see results, you can request a refund within 60 days of purchase.[1]
Shipping options and prices vary depending on location and shipping speed. Customers who purchase AEON from the Perpetua Life website are eligible for a 60-day money-back guarantee.
Cost breakdown: At $68/month (subscription bundle), AEON costs roughly $2.27 per day. At one-time pricing ($85/month), it’s $2.83 per day. Compare that to your daily coffee habit. Still a premium supplement? Yes. But if it genuinely improves healthspan, the ROI could be worth it.
Frequently Asked Questions
The Final Verdict: Is Perpetua Life AEON Worth It?
Perpetua Life AEON is a well-formulated, research-backed longevity supplement with therapeutic doses of 11 potent ingredients. The liposomal delivery system addresses a real absorption problem, and the day-night split makes biological sense for circadian rhythm support.
Does it work? Based on my experience and aggregated user data: Yes, for most people over time. You’ll likely notice improved energy, better sleep, and enhanced resilience to stress. Skin and deeper anti-aging effects require months to years of consistent use.
Is it worth the price? This is where it gets personal.
Who AEON is Perfect For:
- Serious biohackers willing to invest $68-85/month in a comprehensive longevity stack
- Individuals 40+ with declining NAD+ levels looking for multi-pathway support
- People who value convenience and want 11 ingredients in two formulas instead of 11 separate bottles
- Those committed to LONG-TERM use (6+ months minimum)
Who Should Probably Pass:
- Budget-conscious users – there are cheaper NAD+ boosters available
- People seeking instant results—longevity supplements work slowly
- Individuals who only want simple NMN supplementation—you’re paying for ingredients you may not need
- Anyone with difficulty swallowing large capsules
My take? If you’re over 40, serious about longevity, and can afford the investment, AEON is one of the most robust formulas available. The science is sound, the dosages are competitive, and user results (including mine) support the claims.
But if you’re on the fence or on a budget, start with standalone NMN or a less expensive NAD+ booster. You can always upgrade to AEON later.
The longevity game is measured in decades, not days. Choose the strategy you can sustain.
Get Started with Perpetua Life AEON (10% Off with Code FOODNURISH)
References
- [1] Perpetua Life – “AEON: Advanced NAD+ Support System” – Accessed 2025
- [2] NIH National Library of Medicine – “Nicotinamide Mononucleotide (NMN) Supplementation Promotes NAD+ Biosynthesis in Healthy Middle-Aged Adults” – February 2022
- [3] Reddit – “Perpetua Life AEON User Experiences and Reviews” – Various dates 2024-2025
- [4] Journal of Gerontology – “Fisetin as a Senotherapeutic Agent: Biopharmaceutical Properties and Crosstalk between Cell Senescence and Neuroprotection” – January 2022
- [5] Perpetua Life Official Store – “AEON Pricing and Subscription Options” – Accessed 2025
- [6] Reddit r/Supplements – “Blood Sugar Concerns with NAD+ Boosters” – 2024
- [7] Cell Metabolism – “α-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice” – September 2020
- [8] Frontiers in Aging Neuroscience – “Pterostilbene and Cognitive Function: A Systematic Review” – 2021
- [9] Phytomedicine – “Apigenin and Its Anxiolytic Effects” – June 2019
- [10] Journal of Functional Foods – “Liposomal Curcumin and Its Application in Cancer” – May 2019
- [11] EBioMedicine – “Senolytic Therapy: A Novel Approach to Targeting Cellular Senescence” – July 2019
- [12] BMJ – “Vitamin D Supplementation and Mortality: Meta-Analysis of Randomized Controlled Trials” – April 2014
- [13] European Journal of Clinical Nutrition – “Liposomal Encapsulation Technology: Enhanced Bioavailability of Hydrophobic and Hydrophilic Nutrients” – October 2019
- [14] Aging – “Prospective longevity study of a gut-conditional, Ca-AKG-based formulation” – August 2021
- [15] Frontiers in Nutrition – “Impact of liposomal delivery on coenzyme Q10 absorption” – September 2025
- [16] PMC – “Liposomal delivery enhances absorption of vitamin C into plasma and leukocytes” – September 2024
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