Dr. Brad Stanfield Supplements: His Complete Protocol & Stack Review

A complete breakdown of the supplements and medications Dr. Stanfield takes, those he avoids, and the evidence behind his choices.

Dr. Brad Stanfield's evidence-based supplement recommendations displayed with smartphone, notes, and healthy foods on marble countertop

Dr. Brad Stanfield has carved out a unique space in the longevity community. When searching for Dr. Brad Stanfield supplements, you aren’t looking for magic pills; you are looking for the “voice of reason.”

Unlike influencers pushing $500 monthly protocols based on mouse studies, Stanfield is a practicing New Zealand General Practitioner who prioritizes clinical human data above all else.

His approach is ruthlessly pragmatic: if a supplement fails in human trials, it gets CUT immediately.

A 3D pyramid illustration representing Dr. Brad Stanfield's health philosophy, showing Sleep as the large foundation, followed by Exercise and Diet, with Supplements as the smallest section at the top.
Dr. Stanfield’s “Pyramid of Health” prioritizes Sleep and Exercise as the foundation of longevity, with supplements serving only as the final 5%.

His philosophy follows a strict hierarchy: Sleep > Exercise > Diet > Supplements.

If you aren’t sleeping 7-8 hours and lifting weights, no amount of NMN will save you.

But for those who have the basics dialed in, Stanfield has developed a specific, evidence-based protocol to lower biological age and extend healthspan.

This guide breaks down exactly what he takes, the scientific reasoning behind it, and why he famously abandoned “hype” molecules like Resveratrol.

The Core “Dr. Brad” Stack (What He Actually Takes)

Stanfield’s daily routine has shifted from a handful of random pills to a consolidated approach. He realized that to get effective doses of the heavy hitters—like Creatine and Collagen—you cannot rely on capsules. You need powder.

1. MicroVitamin+ Powder (The Foundation)

This is the cornerstone of his current regimen. 

Dr. Stanfield formulated this because taking effective dosages of these ingredients separately would require swallowing 20+ pills every morning.

The powder includes a base of essential vitamins and minerals. The most notable are Vitamin D3 (1000 IU) and Vitamin K2 (90 µg). These two vitamins work in synergy.

Vitamin D3 enhances the absorption of calcium from the diet, but Vitamin K2 is responsible for directing that calcium into the bones and teeth, rather than allowing it to accumulate in arteries and soft tissues, where it can cause calcification and cardiovascular problems.

Dosage: 1 Scoop Daily (mixed in water/smoothie)

The “Macro” Ingredients:

  • Creatine Monohydrate (5g): Most people think this is just for bodybuilders. Stanfield takes it for cognitive function and to prevent sarcopenia (age-related muscle loss).
  • Collagen Peptides (12.5g): Key for skin elasticity and joint health. (Ed. note: Most collagen pills only have 0.5g. You need at least 10g for clinical benefit, which is why he uses powder.)
  • Psyllium Husk (2.5g): Soluble fiber to bind LDL cholesterol and improve gut health.
  • Taurine (1g): Supports metabolic health and mitochondrial function.

The “Micro” Ingredients (Included in the powder):

  • Full Multivitamin Profile: Includes Vitamin D3 (1000 IU), Vitamin K2 MK-7 (90mcg), Zinc (8.25mg), Magnesium Taurate, and a full B-Complex (Methyl-B12, Methyl-Folate).
  • Trimethylglycine (TMG) (500mg): Acts as a “methyl donor” to lower homocysteine levels. High homocysteine = increased risk of cardiovascular disease [1].
  • Hyaluronic Acid (200mg): He cites a study showing a significant reduction in wrinkles with oral supplementation.

CLARIFICATION: This is not just a creatine or collagen powder. It is a complete replacement for a multivitamin.

2. Omega-3 Fatty Acids

Dosage: ~1g Daily (EPA/DHA combined)

“Why such a low dose?” you might ask, considering some biohackers take 4g+.

Stanfield limits his intake based on the STRENGTH Trial, which showed that high doses (4g/day) of carboxylic acid formulation Omega-3s were associated with an increased risk of Atrial Fibrillation (irregular heartbeat) [2].

He stays in the “Goldilocks” zone – enough for benefit, low enough to minimize risk.

He emphasizes the VITACOG Trial, which found that B-vitamins (like the B12 in his MicroVitamin+) only slowed brain atrophy in people who had sufficient Omega-3 levels. If your Omega-3 index is low, B-vitamins might not protect your brain.

3. The Sleep Stack (“Sleep by Dr Brad”)

Stanfield is obsessive about sleep. Previously, he took these ingredients separately, but he has since launched his own formula called Sleep by Dr Brad.

A single bottle of the supplement Sleep by Dr. Brad
Sleep by Dr. Brad

Dosage: 4 Capsules, 1-2 hours before bed.

The Ingredients:

  • Melatonin (300mcg): Note the unit—MICROGRAMS, not milligrams. Most supplements sell 3mg or 5mg (which is 10-15x higher). Stanfield argues these doses are unnaturally high and cause receptor desensitization. 300mcg mimics the natural pineal gland secretion.
  • Magnesium Glycinate (126mg elemental): Magnesium supports relaxation, and the “Glycinate” form is gentle on the stomach.
  • Glycine (2.5g): Glycine helps lower core body temperature, which is a chemical signal to the brain that it is time to sleep.

The Prescription Protocol (Not Supplements)

We must distinguish between what you can buy at a health store and what Dr. Stanfield takes under medical supervision.

  • Lipid Management (Rosuvastatin + Ezetimibe): Stanfield takes a low-dose statin (5mg) combined with Ezetimibe (10mg). His goal is to crush ApoB (the particle that causes plaque) as low as possible.
  • Hair Loss (Finasteride 1mg): He uses this to block the conversion of Testosterone to DHT, preventing male pattern baldness. He cites long-term safety data to counter the online fear-mongering regarding side effects.

What about Rapamycin?

Dr. Stanfield is currently running a clinical trial on Rapamycin. While he is arguably the face of Rapamycin interest on YouTube, he has stated he does NOT recommend it for public use yet. The risk of immune suppression is real, and the optimal dosing frequency for humans is currently unknown.

What He STOPPED Taking (And Why)

This is where Stanfield upsets the apple cart. He has publicly abandoned several “darlings” of the longevity world after reviewing new data.

A timeline graphic illustrating Dr. Brad Stanfield discarding fading bottles of NMN and Metformin while keeping a structured container of MicroVitamin.
The evolution of the protocol: Why Dr. Stanfield abandoned “hype” molecules like NMN and Metformin in favor of proven basics.

1. NMN & Resveratrol

For years, these were the non-negotiables of longevity. Stanfield dropped them both.

  • Resveratrol: The Interventions Testing Program (ITP)—the gold standard for longevity studies in mice—showed ZERO lifespan extension with Resveratrol. The original “sirtuin activation” study was likely flawed due to a fluorescent dye artifact [3].
  • NMN (Nicotinamide Mononucleotide): While it boosts NAD+ levels, Stanfield argues there is no evidence this translates to increased healthspan in humans. Furthermore, there is a theoretical cancer risk: cancer cells consume NAD+ voraciously. Without clear benefit, the risk isn’t justified.

2. Metformin

Once dubbed “aspirin for anti-aging,” Metformin is now out of his protocol for healthy individuals.

  • The Reason: Metformin blunts the mitochondrial adaptations to exercise.
  • The Math: Exercise = Potent longevity drug. Metformin + Exercise = Less effective exercise.

3. Sulforaphane Supplements

While he advocates for the benefits of Sulforaphane, he stopped taking it in pill form due to stability issues. He now prefers getting it from natural sources like broccoli sprouts.

4. Vitamin A & E

He avoids supplementing these antioxidants. Large meta-analyses have suggested that supplementing with Vitamin A and E can actually INCREASE all-cause mortality [4]. They may interfere with the body’s natural oxidative signaling (“hormesis”) that triggers repair mechanisms.

5. Quercetin & Fisetin

These compounds are known as senolytics, which are thought to clear out old, dysfunctional (senescent) cells. He stopped taking them after data from the highly respected Interventions Testing Program (ITP), which tests compounds in mice, showed no lifespan benefit.

6. Ashwagandha, Sulforaphane, Apigenin

These were removed due to a lack of convincing human data for his specific health goals or, in the case of Ashwagandha, a personal choice to stop.

Dr. Stanfield’s Product Line: A Critical Review

Dr. Stanfield sells his own supplements. Is this just a cash grab, or is it legitimate? Let’s break down the value proposition.

1. MicroVitamin+ (Powder)

  • Cost: ~$80 USD / month.
  • What you get: A full Multivitamin + 5g Creatine + 12.5g Collagen + TMG + Fiber.
  • Verdict: If you try to buy high-quality versions of all these ingredients separately, you will spend roughly $60 to $70 and have to open 6 different jars every morning. For an extra $10 to $20, you get the convenience of a single scoop and third-party purity testing. It is a solid value for those who hate pill fatigue.

PRO TIP: If you want to drop that monthly cost, you can use this link to automatically apply a 5% discount. Alternatively, enter code PAVLOS8777750 at checkout. Note that this is valid for new customers only.

2. Sleep by Dr Brad

  • Cost: ~$39 USD / month.
  • What you get: Melatonin (300mcg), Magnesium Glycinate, Glycine (2.5g).
  • Verdict: This is unique because of the 300mcg Melatonin. It is nearly impossible to find this low dose in stores (most are 3mg+).

Buying his sleep stack is actually cheaper or price-neutral compared to buying the ingredients separately, and you get the correct “micro” dose of melatonin without having to split pills. To make it strictly cheaper than the DIY route, you can save an extra 5% off storewide here (or use code PAVLOS8777750).

Future Protocol (Age 45+)

GlyNAC: Stanfield has indicated he plans to introduce GlyNAC (Glycine + N-Acetyl Cysteine) to his protocol once he hits 45.

Why wait?

Younger bodies are efficient at producing Glutathione (the master antioxidant). As we age, this production drops. Supplementing GlyNAC helps restore these levels, reducing oxidative stress and mitochondrial dysfunction in older adults [5].

Rapamycin & 17-Alpha Estradiol: While these are generating significant excitement in longevity circles, he believes their use should currently be confined to clinical trials ONLY.

(Ed. note: This responsible stance prioritizes safety over speculation, a stark contrast to the “biohacker” ethos of self-experimentation with powerful, under-researched compounds.)

Building Your Own Evidence-Based Protocol

Dr. Stanfield’s protocol offers a clear blueprint: start with the non-negotiable foundations of lifestyle (diet, exercise, sleep), then add a select few supplements that have strong human data to support their use.

His core, high-confidence choices are his custom MicroVitamin+ powder, Omega-3, and his targeted sleep stack. His willingness to publicly abandon popular supplements like NMN when the data doesn’t meet his high standards is perhaps the most important lesson.

If you have the budget, his MicroVitamin+ (or a generic stack of Creatine, Collagen, and TMG) provides the best structural and metabolic insurance policy available today. (New customers can use code PAVLOS8777750 for 5% off the total order).

Always speak with your doctor before beginning any new supplement or medication regimen. Use this guide as a starting point for your own research and a productive conversation with a trusted healthcare professional.

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